The Medicines and Healthcare products Regulatory Agency (MHRA) have launched an investigation into the safety of metal-on-metal hip replacements after fears that they could cause long-term complications. In particular they are  investigating the potential long-term toxicity of metal-on-metal hip replacements.

Problems with metal on metal hip replacements can occur when friction between the metal ball and the cup causes tiny metal filings to break off and potentially seep into the blood.

The MHRA has advised that all patients with metal on metal hip replacements should have annual check-ups and be followed up for five years. In addition they recommend that those experiencing pain should be tested for levels of cobalt and chromium in their blood and an MRI or ultrasound scan to check for soft tissue reactions.

The MHRA is working closely with the England and Wales National Joint Registry, the British Hip Society and the British Orthopaedic Association to review relevant safety information as it arises and will take action to provide further advice with people with implants if they identify the need.

Most hospitals will have contacted patients with a metal-on-metal hip, but anyone with outstanding concerns should contact their GP or hospital department.

The British Hip Society (BHS) discussed the latest research on the devices at its annual meeting, which took place in Manchester last week (February 29th to March 2nd). They have now called for large diameter metal-on-metal hip implants to be avoided when performing total hip replacement surgery.

Arthritis Research has produced a useful Q&A on the issue if you would like to read more.