NASS members have long been supporting research at Oxford University to find the genes that make people more likely to develop ankylosing spondylitis (AS). It has already led to major advances that are leading to new ideas about possible treatments. As many as 20 different genes may be involved but only a few have yet been identified. These include HLA-B27, the interleukin 23 receptor (IL23R) and ERAP1 which used to be known as ARTS1.
The unit in Oxford now has a one off chance to try to find the other genes involved in AS thanks to generous funding from the Wellcome Trust. But this means that we need to recruit an extra 2,000 people with AS before the end of 2012. To take part all you will need to do is answer a few simple questions about your AS and provide a sample of your saliva in a special pot that is returned to the researchers through the post. You simply dribble saliva into the pot and do this at least 30 minutes after you have last eaten. It's completely painless and quick. You don't need to go to your GP and you will be sent all the items you need by the study nurse through the post.
If you haven't already taken part and you would like to find out more information please contact Claire Farrar, the research nurse by email.
Thank you for your help in helping research to change the future for people with AS.
Last reviewed: January 2012